NUMB3RSisadramaaboutFBIagentDonEppesRobMorrow,whorecruitshismathematicalgeniusbrother,CharlieDavidKrumholtztohelptheBureausolveawiderangeofchallengingcrimesinLosAngelesThetwobrotherstakeonthemostconfoundingcriminalcasesfromaverydistinctiveperspective　　　　Inspiredbyactualcases,theseriesdepictshowtheconfluenceofpoliceworkandmathematicsprovidesunexpectedrevelationsandanswerstothemostperplexingcriminalquestions　　　　AdedicatedFBIagent,Doncouldn'tbemoredifferentfromhisyoungerbrother,Charlie,abrilliantmathematicianwho,sincehewaslittle,hasyearnedtoimpresshisbigbrotherAsaseasonedinvestigator,Dondealsinhardfactsandevidence,whereasCharlie,amathprofessorataCaliforniauniversity,functionsinaworldofmathematicalprobabilityandequations　　　　Now,despitetheirdisparateapproachestolife,DonandCharlieareabletocombinetheirareasofexpertiseandsolvesomekillercases